OFFENSE
- WR: Michael Pittman Jr., Ashton Dulin
- LT: Bernhard Raimann, Blake Freeland
- LG: Quenton Nelson, Danny Pinter OR Tanor Bortolini
- C: Tanor Bortolini, Danny Pinter
- RG: Dalton Tucker
- RT: Braden Smith, Matt Goncalves
- TE: Mo Alie-Cox, Drew Ogletree
- TE: Kylen Granson, Will Mallory
- WR: Josh Downs, Anthony Gould
- WR: Alec Pierce OR Adonai Mitchell
- QB: Anthony Richardson, Joe Flacco, Sam Ehlinger
- RB: Jonathan Taylor, Trey Sermon, Tyler Goodson
- Anthony Richardson set a new single-game career-high in passing yards (272) against the New York Jets. He also had two rushing touchdowns, bringing him to seven career rushing touchdowns for the most by a Colts quarterback in his first 11 career starts.
- Josh Downs had five receptions for 84 yards and a touchdown against the Jets.
- Michael Pittman Jr., after missing the Colts' Week 10 game against the Buffalo Bills, returned to action and had five receptions for 46 yards against the Jets.
DEFENSE
- DE: Kwity Paye, Laiatu Latu, Genard Avery
- DT: DeForest Buckner, Taven Bryan, Adetomiwa Adebawore
- NT: Grover Stewart, Raekwon Davis
- DE: Dayo Odeyingbo, Isaiah Land
- WLB: E.J. Speed, Liam Anderson
- MLB: Zaire Franklin, Segun Olubi
- SAM: Grant Stuard, Cameron McGrone
- CB: Samuel Womack III, David Long Jr.
- FS: Julian Blackmon, Rodney Thomas II, Darren Hall
- SS: Nick Cross, Ronnie Harrison Jr.
- N: Kenny Moore II, Chris Lammons
- CB: Jaylon Jones
- Against the Jets, Jaylon Jones had five tackles (three solo) and two passes defensed, tying his single-game career-high in passes defensed.
- Kwity Paye had two sacks against Jets quarterback Aaron Rodgers, including the walk-off sack to end the game.
- Laiatu Latu set a single-game career-high in tackles for loss (2) against the Jets. He also recorded his third career sack and currently is tied for third among all rookies this season in the category.
SPECIALISTS
- P: Rigoberto Sanchez
- PK: Matt Gay
- H: Rigoberto Sanchez
- LS: Luke Rhodes
- KR: Tyler Goodson, Anthony Gould, Ashton Dulin
- PR: Josh Downs, Anthony Gould
- Matt Gay converted on all three field goal attempts against the Jets and one extra point, including a 56-yard attempt to tie Chase McLaughlin (11) for the fourth-most 50-plus yard field goals in team history.
