KANSAS CITY, Mo. — The Indianapolis Colts' top wide receiver and running back are officially available for tonight's primetime matchup against the Kansas City Chiefs.

The Colts have announced their inactives list for tonight's game, and among those who are active that were questionable heading in include T.Y. Hilton and Marlon Mack.

Of the other players labeled questionable heading into the game: starting linebacker Anthony Walker and cornerback Rock Ya-Sin are also active, while safety Rolan Milligan is inactive.

Others who are inactive tonight for the Colts are wide receiver Parris Campbell, tackle/guard Le'Raven Clark, safety Clayton Geathers, safety Malik Hooker, defensive tackle/end Tyquan Lewis and linebacker Darius Leonard.

Hilton, who came into Sunday's action tied for the league lead with four receiving touchdowns, re-aggravated a quad injury just before halftime of the Colts' Week 3 game against the Atlanta Falcons, causing him to miss last Sunday's game against the Oakland Raiders.

Hilton did not practice on Wednesday, but returned for the final two practices as a limited participant. He heads into tonight's game with 20 receptions for 195 yards and four touchdowns; all four of his scores this season have come from within the red zone, tying for the lead league in that category.

Hilton and quarterback Jacoby Brissett will hope to do some damage against a Chiefs defense that will allow some big plays through the air. Kansas City comes into tonight's game having allowed 1,035 passing yards and seven touchdowns through the air, which ranks 19th and 18th in the NFL, respectively.

Mack's potential return, meanwhile, could be huge against a Chiefs defense that is allowing 5.9 yards per carry on the ground through four games, ranking last in the league.

Mack suffered an ankle injury in the second half of last week's game against the Raiders, and he was a non-participant in the first two days of practice this week; he was able to practice fully on Friday, however. The third-year back entered today's Week 5 action ranked fifth in the NFL with 338 rushing yards, and third in the league with 24 first downs.

Walker, Ya-Sin active

The Colts' defense, meanwhile, will need all the firepower it can get tonight against the Chiefs and reigning league Most Valuable Player Patrick Mahomes.

The Kansas City quarterback is off to a torrid pace so far once again in 2019, with 1,510 passing yards and 10 touchdowns to zero interceptions through four games. He's also been sacked just three times.

Walker (shoulder) initially appeared on the Colts' injury report on Friday, though he was still a full participant. Typically Indy's starting MIKE linebacker, Walker has slid over to the WILL linebacker position the last two weeks with All-Pro Darius Leonard out with a concussion; Walker has averaged 12 tackles a game since the switch. Rookie Bobby Okereke has started at MIKE linebacker with Leonard out.

A hip injury led to Ya-Sin being a limited participant in Thursday's practice, and he did not participate on Friday. Head coach Frank Reich told reporters on that the team was "anticipating (Ya-Sin) will be fine," however. The 2019 second-round pick out of Temple has 11 tackles and one pass defensed through his first four NFL games.

Milligan (knee) on Friday was the latest Colts safety to land on the injury report, as the team's two starters at the position — Geathers (concussion) and Hooker (knee) — were already ruled out of tonight's game on Friday.

Milligan being inactive means the Colts have just two safeties — Khari Willis and George Odum — active tonight. Reich and defensive coordinator Matt Eberflus have indicated that cornerback Quincy Wilson could also be utilized at safety if needed; to account for that possibility, the Colts on Friday elevated rookie cornerback Shakial Taylor to the active roster from the practice squad and waived rookie tight end Hale Hentges.