The Colts announced six inactive players for their Monday night Week 16 game against the Los Angeles Chargers at Lucas Oil Stadium:
- TE Kylen Granson (ankle)
- CB Kenny Moore II (ankle)
- C Wesley French
- LB Cameron McGrone
- QB Matt Ryan
- DT Chris Williams
Interim head coach Jeff Saturday said last week Sam Ehlinger would be the Colts' backup quarterback on Monday, with Nick Foles making his first start with the team.