ORCHARD PARK, N.Y. — The Indianapolis Colts (0-1) fell to the Buffalo Bills (1-0), 24-16, in their 2019 preseason opener tonight at New Era Field in Orchard Park, N.Y. Here are updates the updates from tonight's game.

FOURTH QUARTER

— Colts get the run game going a bit with rushes of 21 (Chad Kelly) and 10 yards (Aca'Cedric Ware), and Cole Hedlund knocks in his second field goal of the night, this from 44 yards, to cut Buffalo lead to 17-6 with 12:41 left in the fourth quarter.

— Chad Kelly keeper for 33 yards and the touchdown. Nice moment for the hometown kid here in Buffalo. Cole Hedlund's extra point is good. Colts trail Bills 17-13 with 9:45 left in the fourth quarter. Six-play, 57-yard drive that took 2:26 off the clock.

— Christian Wade with the answer on the first play of the next Buffalo drive. Sixty-five yard touchdown run for the Bills' running back. Buffalo takes 24-13 lead with 9:28 left in the fourth quarter.

— Here we go! Ruling on the field was no pass interference on deep pass attempt to WR Daurice Fountain. Colts challenging there was pass interference. New rule this season. Eventually the ruling on the field stands; incomplete pass "with no substantial pass interference," official says. Interesting nonetheless.

— Cole Hedlund with his third field goal of the night, this from 25 yards out. 24-16 Bills lead over the Colts with 2:43 left in the fourth quarter. Nice 16-play, 69-yard drive that took 6:45 off the clock.

— The Colts fall to the Bills 24-16; are 0-1 in the preseason. Next take on the Cleveland Browns Aug. 17 at Lucas Oil Stadium.

THIRD QUARTER

— Frank Reich in an aggressive mood tonight. Going for it on 4th and 3 from the Buffalo 7-yard line. Second fourth-down try this drive; third of game. But Phillip Walker's pass attempt is off the mark. Turnover on downs.

— Chad Kelly in at quarterback for the Colts. Phillip Walker completed 8-of-18 passes for 85 yards and one interception.

— Bills extend their lead to 14, 17-3, with a 38-yard field goal from Chase McLaughlin. It was a nine-play, 55-yard drive that took 3:34 off the clock. Bills aided by a 15-yard personal foul penalty called on rookie linebacker E.J. Speed.

— That 17-3 lead for the Bills will carry over into the fourth quarter here in Western New York.

SECOND QUARTER

— The Colts have announced that guard Ian Silberman was taken to a local hospital before the game for precautionary reasons for an abdominal medical issue. The team will provide an update when available.

— Bills strike first. Eight-yard touchdown pass from Matt Barkley to tight end Cam Phillips. It's 7-0 Buffalo at the 9:36 mark of the first quarter. 10-play, 46-yard drive that took 5:04 off the clock.

— Carroll Phillips recovers the botched snap at the Buffalo 40, as the ball sails over Barkley's head and bounces into the defensive end's hands. Phillips also has a sack on the night for the Indy defense.

— Colts' offense stays on the field for a 4th and 6 attempt from the Buffalo 34, and Phillip Walker's pass intended for Marcus Johnson is broken up by cornerback Lafayette Pitts. Turnover on downs. Indy unable to take advantage of the freebie turnover.

— Bills running back T.J. Yeldon fumbles the football; forced by cornerback Jalen Collins; safety George Odum on the recovery at the Indy 19. Nice play for the former second-round pick.

— Colts can't capitalize on a takeaway for a second time tonight. Phillip Walker is picked off by safety Dean Marlowe, and Buffalo is now cookin' at the Indy 20-yard line. Four plays later, running back Senorise Perry hopped over the line for a one-yard touchdown run, extending the Bills' lead to 14-0 with 1:12 left in the second quarter.

— Indy gets on the board to end the second half, as Cole Hedlund knocks in his first professional field goal, from 43 yards out, to make it 14-3 Bills. Credit Marcus Johnson with a huge drive for the Colts' offense, as the wide receiver caught two passes for 35 yards, including a very impressive diving catch along the sideline for 20 yards that got the ball to the Buffalo 24-yard line and close enough for Hedlund to knock the kick in.

FIRST QUARTER

— After a couple back-and-forth series from both teams' offenses, the Bills are the first to threaten to put points on the board. But Stephen Hauschka's 34-yard field goal attempt hit off the left upright, constituting another hold for the Indy defense. Defensive end Carroll Phillips added the team's first sack of the preseason earlier in the drive, taking down Bills starting quarterback Josh Allen for a loss of 11 yards.

— The Colts and Bills are scoreless heading into the second quarter. Phillip Walker now in at quarterback for Jacoby Brissett, who completed 2-of-5 passes for 21 yards.

PREGAME

The Indianapolis Colts have released their "will not play" list prior to tonight's 2019 preseason opener against the Buffalo Bills at New Era Field:

• Linebacker Ben Banogu

• Wide receiver Parris Campbell

• Tight end Jack Doyle

• Tight end Eric Ebron

• Wide receiver Penny Hart

• Center Ryan Kelly

• Quarterback Andrew Luck

• Defensive end Jabaal Sheard

• Tight end Ross Travis

• Kicker Adam Vinatieri

• Running back Jordan Wilkins