Boone Grove's Braeton Vann had nine touches for 261 yards and four touchdowns in the Wolves' 40-12 victory over John Glenn.
Mark Brownlee of Elkhart Central carried the football 25 times for 255 yards and two scores in the Blazers' 38-7 win at rival Elkhart Memorial.
Castle's Noah Taylor ran 29 times for 249 yards and four touchdowns in the Knights' 42-14 win over Terre Haute South.
New Palestine's Charlie Spegal had 18 carries for 221 yards and a school-best seven touchdowns in the Dragons' 77-0 blanking of Class 5A state runner-up Kokomo.
John Driscoll of South Bend Saint Joseph ran 19 times for 218 yards and two scores for the Indians in a 26-14 win at Concord.
Chris Harness of Mishawaka rambled 27 times for 217 yards and two scores for the Cavemen in a 35-14 win at Portage.
Western's Kitchel Gifford ran 19 times for 214 yards and six touchdowns in the Panthers; 48-6 win over Twin Lakes.
North Judson's Fletcher Greer recorded 11 carries for 204 yards and two scores for the Bluejays in a 50-6 win against Culver.
Sam Getz of Tri-County accumulated 201 yards on the ground and a touchdown in the Cavaliers' 33-26 setback to Carroll (Flora).
Beech Grove's Teron Washington ran 20 times for 198 yards with a touchdown in the Hornets' 34-26 triumph over Indianapolis Lutheran.
Despite missing the third quarter with leg cramps, Whiteland's Jake Perry still ran for 198 yards and a score in Whiteland's 26-20 upset of top-ranked and defending Class 5A state champion Columbus East.
Evansville Central's Clayton Groves rushed for 197 yards and two scores in the Bears' 42-0 triumph over Greenfield-Central.
Brandon Pruitt of West Noble scampered 27 times for 196 yards and a touchdown in the Chargers' 14-12 decision over Central Noble.
Richmond's Wyatt Byrd racked up 15 carries for 189 yards and four scores in the Red Devils' 34-14 win over Connersville.
Elijah Mahan of Indianapolis Roncalli carried the ball 40 times for 187 yards and two touchdowns in the Rebels' 36-28 loss to Southport.
Southwood's Gabe Lloyd scampered 26 times for 186 yards and two touchdowns in the Knights' 33-0 blanking of Manchester.
Teddy Duneghy of Evansville Harrison needed just nine carries to accumulate 172 yards and three scores in the Warriors' 34-14 win over Crawford County.
Columbus East's Mark McDonald tallied 23 carries for 172 yards and a touchdown for the Olympians against Whiteland.
Bluffton's Everett Johnson carried the ball 13 times for 170 yards and three touchdowns in the Tigers' 40-12 victory against Northfield.
Daveyon Sandford of Goshen ran 130 times for 160 yards and two touchdowns for the RedHawks in their 49-0 blanking of Fairfield.
Quanzell Jones of Beech Grove tallied 18 carries for 158 yards and two touchdowns against Indianapolis Lutheran.
Logansport's Josh Manfred had 155 yards on the ground and two scores in the Berries' 62-0 blanking of Peru.
Michael Johnson of Columbus North ran 23 times for 152 yards and a score in the Bulldogs' 64-7 decision over Franklin.
Warren Central's Romeir Elliott carried 17 times for 150 yards and two scores in the Warriors' 27-15 win at Center Grove.
North Putnam's Chris Murray accounted for 147 yards and two touchdowns in the Cougars' 28-12 win over North Montgomery.
Oscar Grimaldo of Logansport accumulated 137 yards rushing and three scores against Peru.
In addition to running five times for 137 yards with a touchdown, Delphi's Jayden McClain caught two passes for 110 yards and a score for the Oracles in their 61-0 win over Benton Central.
Greensburg's Aaron Black scampered 13 times for 119 yards and four scores in the Pirates' 49-7 victory against Shelbyville.
Matt Harris of Hamilton Southeastern ran two yards for the game winner with 34 seconds left to lift the Royals to a 21-20 win over Lawrence Central.
PASSING GRADES (Top passing performances)
Michael Lindauer of Evansville Memorial was 19-of-34 for 332 yards and two touchdowns in the defending Class 3A state champion Tigers' 30-7 victory over Jasper.
New Haven's Tim Jordan completed 21-of-41 for 323 yards and two scores for the Bulldogs in a 26-20 loss at South Bend Riley.
Southport's Eddie Schott went 19-of-26 for 311 yards and three scores for the Cardinals against Roncalli.
Brownsburg's Ben Easters completed 17-of-23 attempts for 276 yards and four touchdowns in the Bulldogs' 44-13 triumph against Bloomington South.
Along with going 20-of-37 for 269 yards with four touchdowns, Noah Carter of Brown County also ran 14 times for 73 yards and a score in the Eagles' 58-8 win over Edinburgh.
Henry Hesson of Avon went 13-of-19 for 268 yards and two scores for the Orioles in a 44-13 win over Plainfield.
Delphi's Seth Walters was 8-of-11 for 266 yards and five scores against Benton Central.
Justin Williams of South Bend Riley went 16-of-26 for 262 yards and three touchdowns for the Wildcats against New Haven.
Maximus Grimes of Lafayette Jeff was 19-of-34 for 253 yards and four touchdowns in the Bronchos' 38-29 loss at West Lafayette.
Shenandoah's Peyton Starks completed 8-of-20 for 252 yards and three touchdowns in the Raiders' 28-26 loss to Indianapolis Scecina.
West Lafayette's Kyle Adams completed 21-of-32 passes for 249 yards with two scores and also ran for another tally for the Red Devils against West Lafayette.
Garrett's Levi Follett went 15-of-28 for 243 yards and two touchdowns for the Railroaders in their 19-0 blanking of Prairie Heights.
Gibson Southern freshman Brady Allen completed 11-of-18 throws for 242 yards and four scores in the Titans' 48-0 win over Forest Park.
Liam Thompson of North Central (Indianapolis) was 10-of-17 for 241 yards with two touchdowns and ran for a third tally in the Panthers' 31-7 win over Fishers.
Karson Goodman of Mooresville went 10-of-24 for 236 yards with three touchdowns in the Pirates' 46-7 win over Lebanon.
Sam Azbell of Heritage Christian was 16-of-23 for 231 yards and six touchdowns in the Eagles' 44-14 decision over Indianapolis Manual.
Columbus North's Trenton Kelley went 8-of-15 for 227 yards and three scores against Franklin.
Max Ayers of Indianapolis Scecina was 17-of-21 for 223 yards and three touchdowns for the Crusaders against Shenandoah.
Indianapolis Cathedral's Orin Edwards went 17-of-22 for 221 yards and two scores for the Irish in a 31-7 win over Noblesville.
Tyson Hanley of Mount Vernon (Fortville) finished 13-of-16 for 221 yards and two touchdowns in the Marauders' 43-14 triumph over Hamilton Heights.
Anderson's Xander Stokes threw for 218 yards and one touchdown in the Indians' 31-9 loss to Yorktown.
Jason Graves of Indianapolis Pike was 18-of-27 for 201 yards and a touchdown for the Red Devils in a 27-19 win over Zionsville.
Western Boone's Spencer Wright completed 12-of-19 passes for 194 yards and three scores in the Stars' 50-12 win over Sheridan.
Ryan Caldwell of Bremen went 12-of-21 for 191 yards and four touchdowns in the Lions' 34-7 victory over Tippecanoe Valley.
New Castle's Drew Barber was 9-of-18 for 190 yards and four touchdowns in the Trojans' 42-12 win over Franklin County.
Lapel's Cole Alexander completed 9-of-16 for 181 yards with two touchdowns and ran for another score in the Bulldogs' 50-8 victory over Elwood.
Eli Wirthop of Evansville Reitz went 7-of-12 for 174 yards and two touchdowns and also ran 12 times for 183 yards and a score in the Panthers' 41-35 win over Henderson County.
South Central's Kyle Schmack tossed for 174 yards with one score and ran for 59 yards and one tally in the Satellites' 30-17 loss to Triton.
Vincennes Lincoln's Evan Combs was 7-of-11 for 171 yards and three touchdowns in the Alices' 44-11 win over Owen Valley.
Trey Heidlage of Batesville not only completed 11-of-15 passes for 159 yards and three touchdowns, he also carried the ball 12 times for 103 yards and one score in the Bulldogs' 40-0 blanking of Jennings County.
Tipton's K.J. Roudebush finished 9-of-18 for 158 yards with two touchdowns and rushed eight times for 56 yards and three scores in the Blue Devils' 48-7 win over Madison-Grant.
Culver Academy's Max Miller went 7-of-17 for 143 yards with one touchdown and ran 10 times for 52 yards in the Eagles' 28-6 win over LaVille.
Heisman Skeens of Mississinewa was 8-of-11 for 143 yards and one score and ran 24 times for 123 yards and a touchdown for the Indians against Pendleton Heights.
Yorktown's Reid Neal went 12-of-17 for 142 yards and three scores for the Tigers against Anderson.
Along with tossing for 141 yards and three touchdowns, Eastside's Joe White returned an interception for another tally in the Blazers' 46-13 victory over Heritage.
In addition to throwing for 133 yards and two scores, Triton's James Snyder also ran for 84 yards against South Central.
Bryce Hayman of Michigan City completed 10-of-15 passes for 120 yards and five touchdowns and also ran for 83 yards in the Wolves' 53-0 blanking of Griffith.
Heritage Hills' Cole Sigler proved to be a double threat by completing 5-of-6 attempts for 76 yards with a touchdown and running 12 times for 139 yards and two scores in the Patriots' 45-7 victory over Mount Vernon (Posey).
West Central's Camron Neeley completed all three of his passes for 58 yards and two scores and also ran for 169 yards and three touchdowns in the Trojans' 72-6 victory against Caston.
In addition to throwing a touchdown pass and running 18 times for 183 yards and three scores, Pioneer's Jack Kiser also came up with a pair of interceptions in the defending Class 1A state champion Panthers' 44-0 blanking of Lewis Cass.
WHAT A CATCH (Top receiving performances)
Carmel's Sam Rogers was on the receiving end of the game-winning 21-yard touchdown pass from Tyler Trent with 28 seconds left as the Greyhounds downed two-time defending Class 6A Kentucky state champion Trinity, 24-21, to end their 30-game winning streak.
Chris White of South Bend Riley caught five passes for 151 yards and a touchdown against New Haven.
Blake Carroll of Delphi hauled in four receptions for 147 yards and four scores against Benton Central.
Mooresville's Jon Eineman recorded five catches for 142 yards with two touchdowns and also returned a punt 63 yards for another tally against Lebanon.
Jack Marksberry of Trinity Lutheran racked up f12 catches for 134 yards and one score in the Cougars' 27-14 loss to Indianapolis Tindley.
Brownsburg's Bryce Kirtz had five receptions for 119 yards and three touchdowns for the Bulldogs against Bloomington South.
Luke Bumbalough of New Castle caught five passes for 108 yards and four touchdowns against Franklin County.
SPECIAL PERFORMERS (Top performances on defense and special teams)
Evansville Memorial's Brock Combs recorded 12 tackles against Jasper.
Hayden Snider of NorthWood came up with a 102-yard interception return for a score in the Panthers' 26-0 win at Jimtown.
Bloomington North's Xavier Trueblood had a 73-yard punt return for a touchdown in the Cougars' 31-15 win at Greenwood.
In addition to running for a pair of touchdowns, New Prairie's Dan Tyler also returned a fumble 67 yards for another tally in the Cougars' 42-14 win over LaPorte.
Pendleton Heights' Nick Taylor converted an 18-yard field goal with 18 seconds left to lift the Arabians over Mississinewa.
Hobart's Tyler Turley came up with a pair of fumble recoveries, one of which he returned 47 yards for a score in the Brickies' 10-9 win at Chesterton.
Justen Ramsey of Merrillville recorded a fumble recovery, interception, and batted down a pass for the Pirates in their 20-14 win over Andrean.
Cade Laughman of Bloomington North had a 36-yard fumble return for a score against Greenwood.
South Bernd Riley's Kobe Luuga snatched a pair of interceptions against New Haven.