INDIANAPOLIS — The Indianapolis Colts on Sunday had a prime opportunity to, for the first time all season, take the reigns of the AFC South Division and run with it.

And, up two scores halfway through the fourth quarter of Sunday night's game against the Houston Texans, it looked like the Colts were going to do just that.

But the momentum quickly shifted the home team's way. Before the Colts knew it, the Texans had tied the game at 23 in the final seconds, and provided them with a dreadful flight home after nailing a game-winning field goal in overtime to win, 26-23.

To make matters worse, Indianapolis (2-4) was the only AFC South team to lose on Sunday. The Jacksonville Jaguars slipped by the Chicago Bears, 17-16, while the Tennessee Titans continued to roll, defeating the Cleveland Browns, 28-26.

Now, the Colts are at the bottom looking up instead of the other way around. They take on the Titans next week looking to climb their way back into a better position in the division.

But before the Colts completely turn the page and hope for better results against the Titans, let's take a comprehensive look around the AFC South action during Week 6 of the 2016 regular season, via the AP:

• Jacksonville Jaguars 17, Chicago Bears 16:
Blake Bortles threw for 271 yards and hit a slipping Arrelious Benn for a 51-yard touchdown in the closing minutes, lifting the Jacksonville Jaguars to a 17-16 victory over the Chicago Bears on Sunday.

The Jaguars (2-3) wiped out a 13-0 deficit in the fourth quarter in a matchup of last-place teams. And the go-ahead touchdown might have been helped by the oft-criticized turf at Soldier Field.

Benn slipped as he caught a slant and so did Tracy Porter as he tried to tag the receiver. That allowed Benn, who spent the past three seasons on injured reserve, to get up and run untouched for his first touchdown in five seasons.

That gave the Jaguars a one-point lead with 2:49 left and sent the Bears (1-5) to another loss after they dropped the previous game to Indianapolis on a late TD pass by Andrew Luck. Chicago came up short despite racking up 389 yards.

The Bears' Brian Hoyer threw for 302 yards - his fourth straight 300-yard game filling in for the injured Jay Cutler (sprained right thumb).

Cameron Meredith had 11 catches for 113 yards. Alshon Jeffery added 93 yards receiving.

Willie Young had two sacks for Chicago. Porter intercepted Bortles in the end zone early on, but Chicago fell to 2-9 at home in two seasons under coach John Fox.

Bortles completed 20 of 33 passes with a touchdown and interception. Allen Hurns added 74 yards receiving, and Chris Ivory ran for a TD for Jacksonville.

• Tennessee Titans 28, Cleveland Browns 26:
Marcus Mariota threw for 284 yards and three touchdowns, and the Tennessee Titans held on to beat the Cleveland Browns 28-26 Sunday for their second straight victory - the first time they've won consecutive games since the end of the 2013 season.

The Titans (3-3) matched their win total for all of last season when they went 3-13 and wound up with the No. 1 draft pick overall. They also beat a team other than Jacksonville on their own field for the first time since the 2013 season finale and improved to 3-16 in Nashville.

Cleveland (0-6) now is mired in its worst start since 1999 when the Browns lost their first seven as an expansion franchise.

Not that the Titans care after losing to the Browns each of the past two seasons, especially with the Browns nearly pulling off another thrilling comeback. They made NFL history here in 2014 rallying from 25 points down to win.

This time, they trailed 28-13 when Cody Kessler hit Terrelle Pryor Sr. for a 5-yard TD with 2:07 left, but his pass on the 2-point conversion failed. The Browns recovered the onside kick, and Duke Johnson Jr. scored.

The Browns kicked another onside kick, yet Andre Johnson recovered the ball for Tennessee.

• Houston Texans 26, Indianapolis Colts 23 (OT):
Nick Novak made a 33-yard field goal in overtime to give the Houston Texans to a 26-23 comeback victory over the Indianapolis Colts on Sunday night.

Brock Osweiler threw a 36-yard pass to Jaelen Strong to get Houston to the 12 and Novak's field goal came two plays later.

Indianapolis (2-4) got the ball first in overtime, but Benardrick McKinney sacked Andrew Luck on third down to force a punt.

Osweiler shook off a tough start to throw two touchdown passes in less than 2 minutes in the fourth quarter as Houston (4-2) erased a 14-point deficit to tie it at 23 with 54 seconds left. He found Lamar Miller on a 10-yard catch-and-run TD with 2:47 remaining and, after a stop by the defense, connected with C.J. Fiedorowicz on a 26-yarder that tied it.

Houston's defense forced a punt by Indianapolis to send it to OT.

Luck had a 22-yard touchdown throw in the first quarter and pushed the lead to 20-9 when he dashed into the end zone untouched on a 14-yard run early in the fourth.

Miller scored his first touchdown as a Texan on a 1-yard run on Houston's first drive of the second half, but the extra point failed to leave the Texans down 13-9.

The Texans stopped the Colts on fourth down after that, but Osweiler's pass was intercepted two plays later. Luck's TD run came on the next drive.

The Colts built led 13-0 in the second quarter after two field goals by Adam Vinatieri and a touchdown catch by Jack Doyle. Osweiler and Houston's offense struggled to get going and early and Osweiler had negative-9 yards passing in the first quarter. The Texans cut it to 13-3 at halftime on Novak's 27-yard field goal.