COLTS 41, SAINTS 10 Reggie Wayne's first touchdown against the Saints in the season opener gave the Colts a two-touchdown lead. His second all-but secured the victory. Wayne, who made his first Pro Bowl appearance the season before, finished the season opener with seven receptions for 115 yards, including this 45-yarder that gave the Colts a 34-10 lead and also was quarterback Peyton Manning's third touchdown pass of the game.